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Kossiakoff, Anthony
One or more keywords matched the following properties of Kossiakoff, Anthony
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keywords Protein Engineering
One or more keywords matched the following items that are connected to Kossiakoff, Anthony
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Academic Article Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Academic Article Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity.
Academic Article Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution.
Academic Article The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry.
Academic Article Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Academic Article Molecular recognition in biological systems: from activation to inhibition.
Academic Article High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.
Academic Article Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold.
Academic Article An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells.
Academic Article Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.
Academic Article Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
Academic Article A polar ring endows improved specificity to an antibody fragment.
Academic Article Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
Academic Article Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
Academic Article An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.
Award or Honor Receipt Director Department of Protein Engineering
Academic Article Structure of an AMPK complex in an inactive, ATP-bound state.
Grant Energetics of cytokine-induced receptor signaling
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  • Protein Engineering